Abstract: Tillodontia is an old and extinct mammalian order, ranging from Paleocene to Eocene in North America and Eurasia. It is also a small group of Mammalia, including only a single family— Esthonychidae. Fossils in North America have been studied throughly and five genera (Esthonyx, Trogosus, Tillodon, Megalesthonyx and Azygonyx) were recorded. One or two genera (Plesiesthonyx—someone thought it was a synonym of Esthonyx, and Franchaius) were reported from Europe. In Asia, three Paleocene genera Meiostylodon, Interogale and Anchilestes) apart from four Eocene genera (Adapidium, Kuanchuanius, Chungchienia and Basalina) have been studied in the past In the present paper was described a new genus and species, Huananius youngi from the Paleocene of Nanxiong Basin, Guangdong Province.